Effect of tranilast on restenosis after coronary angioplasty
نویسندگان
چکیده
منابع مشابه
Clinical trials of restenosis after coronary angioplasty.
Since its introduction more than 10 years ago, coronary angioplasty has been limited by a 30-40% incidence of restenosis, typically developing within 3-6 months of the procedure.12 The interactive biological processes responsible for re-stenosis have generally been attributed to varying degrees of three pathological mechanisms. First, depending on the relative fibrocellular, sclerotic, and calc...
متن کاملImpact of cilostazol on restenosis after percutaneous coronary balloon angioplasty.
BACKGROUND Restenosis after percutaneous transluminal coronary (balloon) angioplasty (PTCA) remains a major drawback of the procedure. We previously reported that cilostazol, a platelet aggregation inhibitor, inhibited intimal proliferation after directional coronary atherectomy and reduced the restenosis rate in humans. The present study aimed to determine the effect of cilostazol on restenosi...
متن کاملInfluence of intimal dissection on restenosis after successful coronary angioplasty.
We studied 986 patients who underwent follow-up angiography after successful percutaneous transluminal coronary angioplasty (PTCA) to determine the influence of uncomplicated intimal dissection on restenosis rate. Angiographic evidence of intimal dissection after PTCA was present in 248 patients or 25%. After a mean follow-up time of 7 +/- 5 months (SD) the restenosis rate in patients without i...
متن کاملRestenosis after coronary angioplasty for rapidly progressive coronary stenosis.
OBJECTIVES We hypothesized that percutaneous transluminal coronary angioplasty performed on coronary stenoses that have demonstrated rapid angiographic progression would be associated with a high risk of restenosis. BACKGROUND High rates of restenosis have been documented after percutaneous transluminal coronary angioplasty of unstable lesions and of lesions that recur rapidly after a success...
متن کاملEffect of high dose verapamil on restenosis after peripheral angioplasty.
OBJECTIVES We sought to determine whether treatment with high dose verapamil prevents restenosis in patients at high risk for reoccurrence after successful percutaneous transluminal coronary angioplasty (PTCA). BACKGROUND Restenosis is the major limitation of PTCA. Calcium antagonists have demonstrated some potential as inhibitors of this process. METHODS A total of 98 patients with periphe...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1996
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(96)80665-6